Parkinson's malady is a degenerative illness which comes about because of the moderate and dynamic of neurons in the mind passing. As the region of the cerebrum influenced by the infection assumes an essential part in the control of our developments, individuals are gradually signals hardened, jerky and wild. For instance, wear a Cup to her lips with exactness and adaptability ends up plainly troublesome. These days, the accessible medicines to decrease side effects and moderate the movement of the sickness viably. We can live with Parkinson's for a long time.

Parkinson's-related disorders appear more often around 50 years to 70 years. The average age of onset of the disease to the Canada and France is 57. Initially, the symptoms may be confused with normal aging of the person but as they get worse, the diagnosis becomes more obvious. At the time when the first symptoms appear, it is believed that 60% to 80% of the nerve cells of the black substance (see box) would be already destroyed. So when symptoms appear, the disease has already averaged 5 to 10 years of evolution to low noise

Globally, the disease is diagnosed in more than 300,000 people each year. It seems that the incidence is higher among whites than among blacks, Hispanics or Asians, with the lowest rate for Asians. In Canada, approximately 100,000 people would be with the disease, including 25 000 in Quebec. The number of cases increases with age. Estimated that 65, one out of 100 would be reached, and 2 out of 100 people would be reached to 70 years and more.

At the heart of the disease: a dopamine imbalance

Nerve cells affected by Parkinson's disease lie in an area called "black substance", in the center of the brain. Cells in this area produce dopamine, a chemical Messenger that allows control of the movement but which is also in the sensation of pleasure and desire. The death of the cells of the black substance creates a lack of dopamine. Normally, the control of the movement is the result of a delicate balance between the amounts of dopamine and acetylcholine (another chemical Messenger). If the balance is upset, tremors, stiffness and loss of coordination follows. Conversely, an excess of dopamine could be responsible for symptoms associated with the schizophren

Causes:

What causes the progressive loss of neurons in Parkinson's disease remains unknown in most cases. Scientists agree a set of genetic and environmental factors come into play, not always able to them clearly. According to the current consensus, the environment would play a more important role than heredity, but genetic factors would be predominant when the disease appears before the age of 50. Here are a few environmental factors involved:

• A display early or stretched out to compound toxins or pesticides, including herbicides and bug sprays (for instance, rotenone)

• MPTP, a contaminant now and then heroin medication, can bring about a genuine and irreversible Parkinson's frame all of a sudden. This medication applies its impact in a route like the pesticide rotenone;

• Carbon monoxide or manganese